Natures Aid Methylsulphonylmethane 1000mg.Directions:Take 1 tablet twice per day with food. To obtain maximum benefit from this nutritional supplement, the initial dose can be increased gradually up to 3 tablets twice per day with food. Do not exceed the recommended intake. Ingredients:Methylsulphonylmethane, Anticaking Agents (Silicon Dioxide, Vegetable Source Magnesium Stearate).